Buddy

Rene Russo

Trudy Lintz

Robbie Coltrane

Bill Lintz

Alan Cumming

Dick Croner

Irma P. Hall

Emma

Paul Reubens

Professor Spatz

John Aylward

Joe Bowman

Mimi Kennedy

Mrs. Bowman

Philip Baker Hall

Minister

Dane Cook

Fair Cop

Michael Reid MacKay

Skinny Man

John Ennis

Policeman

Frank Welker

Buddy (voice)

Gary A. Hecker

Buddy (voice)

Frank Collison

Zoo Keeper

Al 'Red Dog' Weber

Barker