Dog's Best Friend

Richard Mulligan

Fred

Shirley Jones

Ethel

Bobcat Goldthwait

Mr. Teller

Adam Zolotin

Wylie Thompson

Ed Asner

Jeep, the Sheep Dog (voice)

Meredith Baxter

Cow (voice)

Jim Belushi

Skippy (voice)

Roger Clinton, Jr.

Pig (voice)

Valerie Harper

Chicken (voice)

Markie Post

Pony (voice)

John Ratzenberger

Goat (voice)

Adrienne Carter

Cynthia Anderson

Kyle Labine

Sam Handel

Tom McBeath

Bob Handel

John Novak

Tim Thompson

David Millbern

Sheriff Pete Ramsey

Lily Shavick

Jenny

Myron Natwick

Principal

Patrick Keating

Police Officer

Alex Doduk

Kid at School

Ellie Harvie

Miss Melrose

David Pires

Various Voices (voice) (uncredited)